Part of the PACT mission is to promote interest in cellular therapy/engineering among physicians and scientists-in-training and to prepare interested individuals for academic careers in cellular therapy/engineering. 

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PACT Web Seminars

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2020 - 2021


May 24, 2021 - The COVID-19 Pandemic: Challenges and Opportunities for Cell Processing Facilities



December 15, 2020 - Contract Manufacturing By and For Academic Institutes



September 3, 2020 - Methods for Cellular Therapies: Tracking Cells In Vivo and Assessing Biodistribution in Patients -- What are your cells doing? Where do they go?




July 17, 2020 - Cell Therapy GTP and GMP Facilities: Design and Operation to Optimize Space to Meet Manufacturing Needs



December 10, 2019 - Guidance for Submission of an Initial IND (Investigational New Drug) Application


September 10, 2019 - Vendor Qualification


February 11, 2019 - Accelerating Your Cell Therapy: A PACT Program Update


November 8, 2018 - Issues Involved in Starting CAR T Cell Manufacturing


June 19, 2018 - Development of GMP Cell Manufacturing of Cardiac Stem Cell


January 16, 2018 - Early Phase Cell Therapy Product Development: Potency Assays


September 26, 2017 - Early Phase Cell Therapy Product Development: Quality in the Lab


June 8, 2017 - Academic and Industry Partnerships - The Next Generation


March 14, 2017 - Accelerating Your Cell Therapy


September 25, 2014 - Challenges and Problem-Solving in Cell Therapy Product Development


May 8, 2014 - Scaling Up Cell Culture: Application of Closed Cell Culture Systems in Clinical Research


November 14, 2013 - Ask the Experts


February 20, 2013 - Cell Therapy for Lung Indications


September 27, 2012 - Protecting Patients from Harm: Ethical, Legal & Policy Responses to Domestic and International Marketing of Clinically Unproven Stem Cell Interventions


February 23, 2012 - Adverse Events and Reactions In Cellular Therapy


August 11, 2011 - Preparing for a FDA Inspection


May 4, 2010 - PACT Web Seminar

The NHLBI and EMMES (PACT Coordinating Center) presentations are available for viewing and printing using the link below. The 5 PACT facility speaker presentations are not available on our website. Please contact the speakers regarding their presentations. Speaker contact information can be found in the Webcast Overview Document embedded in the link below:

May 4, 2010 PACT Webcast Presentation Overview 


October 15, 2009 - Interpretation of the Final Rule: cGMP and Investigational New Drugs Intended for Use in Phase 1 Clinical Trials

July 16, 2009 - Deviation Management of Type 351 and 361 Cell Products


January 29, 2009 - Qualification: Vendor, Equipment and Supplies



November 6, 2008 - Delivering Effective and Result-based Training


July 31, 2008 - Validation Processes


June 25, 2008 - NHLBI Training and Funding Opportunities & Overview of Cell Therapy in Lung Biology and Disease


Februray 21, 2008 - Cryopreservation of Cell Therapy Products


October 11, 2007 - Preparing for an FDA Inspection


July 19, 2007 - Interpreting AABB & FACT Cell Therapy Standards


February 22, 2007 - Adverse Event Reporting (Reporting Issues & Requirements)


October 26, 2006 - Cell Therapy Data Management


July 20, 2006 - Facility Master Files, SOP Development, Deviation Management System


January 19, 2006 - Rapid Release Testing, Product Transportation, Workflow Analysis: Handling Multiple Specimens


July 14, 2005 - CMC Writing, Biological Product Deviation Reporting and Staff Training & Competency Testing


March 31, 2005 - Validation, equipment management and facility cleaning and disinfection

PACT Workshops

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Developing Cellular Therapies

University of Wisconsin - Madison, Waisman Biomanufacturing (WB)
Wisconsin Institutes for Discovery
Madison, WI

April 9, 2013

Manufacturing Cell Therapy Products

Baylor College of Medicine, Center for Cell and Gene Therapy (CAGT)
Pavilion for Women
Texas Children's Hospital
Houston, Texas

Day 1 - October 22, 2012

Day 2 - October 23, 2012

Getting to IND

City of Hope, Center for Applied Technology Development
Argyros Auditorium Duarte, CA

Day 1 - November 10, 2011

  • Larry Couture, PhD- Welcome and introductions
  • Robert Lindblad, MD - PACT, Overview Mission
  • Tina Etcheverry PhD - Critical Considerations for Bioprocessing of Stem Cells for Clinical Use (Presentation not available)
  • Chang-Yi Chen, PhD - Scalable expansion of hES cells in suspension culture (Presentation not available)
  • Timothy Cote, MD, MPH - Regulatory considerations: Early decisions and best practices
  • Martha Reitman, MD - Getting to IND, an Academic Industrial Perspective (Presentation not available)
Translational Development & Scale Up

University of Minnesota, Molecular and Cellular Therapeutics
Continuing Education & Conference Center
St. Paul, Minnesota

Day 1 - October 26, 2010

Day 2 - October 27, 2010

NHLBI PACT Workshop - Cell Therapy for Pediatric Diseases

National Library of Medicine
Lister Hill Center Auditorium
National Institutes of Health
Bethesda, Maryland

Workshop Booklet Day 1 - September 14, 2011

Session 1: Congenital Blood Disorders - Part 1

Session 1: Congenital Blood Disorders - Part 2

Session 2: Neurodegenerative Diseases and Brain Injury

Day 2 - September 15, 2011 Session 3: Regenerative Medicine

NHLBI PACT Workshop - Converging Concepts in Cell Therapy

Natcher Conference Center
National Institutes of Health
Bethesda, Maryland

Day 1 - April 23, 2009

Session 1: T-Regulatory Cells

Session 2: Mesenchymal Stem Cells

Session 3: Antigen-Specific T Cells

Session 4: Engineered T Cells

Session 5: Natural Killer Cells

Day 2 - April 24, 2009

Session 6: Dendritic Cells

Session 7: Cell Trafficking and Imaging Techniques

  • Marianna Sabatino, MD - Imaging and Cell Therapy
  • Erin F. Simonds, PhD Candidate - (Presentation not available)
  • Zhenghong Lee, PhD - (Presentation not available)
  • Eric T. Ahrens, PhD - (Presentation not available
Innovative Cellular Therapies and Methods at GMP Cell Therapy Facilities

University of Pittsburgh Cancer Institute
Immunological Monitoring and Cellular Products Laboratory
Hematopoietic Stem Cell Laboratory 
Herberman Conference Center
Pittsburgh, Pennsylvania

Day 1 - May 5, 2008

Day 2 - May 6, 2008

Design and Operation of GMP Cell Therapy Facilities

University of Minnesota
Molecular and Cellular Therapeutics
Earle Browne Continuing Education and Conference Center 
St. Paul, Minnesota

Day 1 - April 10, 2007

Day 2 - April 11, 2007

Design and Operation of GMP Cell Therapy Facilities

Baylor College of Medicine
Houston, Texas

Day 1 - April 4, 2006

Day 2 - April 5, 2006


Cell Therapy Liaision Meeting
November 23, 2020

Click this link for a summary of the 2020 CTLM meeting with the FDA. Links are embedded in the document to each presentation.


BioCoR, University of Minnesota Biopreservation Core Research presents:

Preservation of Cellular Therapies 2021
(BioCoR's annual short course on preservation of cell therapies)

Dates: May 18 - 19, 2021
Location:  The course will be offered online and potentially in person based on the COVID-19 situation in May 2021.
Course Home Page

Lecture topics:

  • Fundamentals of cryopreservation
  • Protocol development
  • Regulatory issues in cryopreservation
  • Designing a storage facility
  • Containers, reagents and equipment 
  • Emerging issues in preservation of cell therapies
  • Clinical cell cryopreservation
  • Quality control


The course is designed for a wide range of participants.  The course is appropriate for manufacturing engineers, managers as well as technicians who work with cell-based products: cell banks, biobanks, companies that use cell-based assays, cell therapy companies, regenerative medicine companies, hospitals or cell therapy laboratories.  The course material is designed for those who have little experience with preservation as well as those proficient in preservation who are interested in improving their practices.


Allison Hubel, PhD is Professor of Mechanical Engineering and Director of the Biopreservation Core Resource (BioCoR,, a national resource in biopreservation. 

Diane Kadidlo received her B.S. from Iowa State University.  She has served as the Supervisor for the University of Minnesota Medical Center Clinical Cell Therapy Laboratory since 1996 overseeing the production of cell and tissue products.  

David McKenna, MD is a Professor of Laboratory Medicine & Pathology at the University of Minnesota where he holds the American Red Cross Chair in Transfusion Medicine.  He is the Scientific and Medical Director of Molecular & Cellular Therapeutics.

Ian M Pope, PhD, MBA, BSc is the Global Director of Cryo Solutions at Brooks Life Sciences. Ian has worked in the area of cryogenic systems for over 25 years, His expertise lies in the area of the practical application of cryogenics to the storage and preservation of biological materials. 

Fran Rabe has over 20 years of experience working in the areas of tissue and cell quality assurance and regulatory compliance.  She currently oversees the quality assurance aspect of operations at the University of Minnesota Molecular and Cellular Therapeutics (MCT) Facility.

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